Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,156
Tocris Bioscience™ A 410099.1 amide-PEG4-amine
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IAP ligand with PEG linker and terminal amine for onward chemistry
1,157
Tocris Bioscience™ LY 379268
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CAS: 191471-52-0 Molecular Formula: C7H9NO5
| CAS | 191471-52-0 |
|---|---|
| Molecular Formula | C7H9NO5 |
1,158
Tocris Bioscience™ JZL 195
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CAS: 1210004-12-8 Molecular Formula: C24H23N3O5
| CAS | 1210004-12-8 |
|---|---|
| Molecular Formula | C24H23N3O5 |
1,159
Tocris Bioscience™ PSNCBAM-1
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CB1 receptor negative allosteric modulator
| Inhibitors | PSNCBAM-1 |
|---|---|
| Product Type | PSNCBAM-1 |
| Molecular Weight (g/mol) | 392.88 |
| Purity | >99% |
1,160
Tocris Bioscience™ GBR 12909 dihydrochloride
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Selective DA uptake inhibitor; also σ ligand
| CAS | 67469-78-7 |
|---|---|
| Solubility | Soluble to 50mM in DMSO |
| Chemical Name or Material | 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C28H32F2N2O.2HCl |
| Formula Weight | Observed MW: 523.49 |
| Assay Percent Range | >98% |
1,161
Tocris Bioscience™ EPPTB
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Trace amine 1 (TA1) receptor antagonist/inverse agonist
| Target | Trace Amine 1 (TA1) Receptor Antagonists |
|---|---|
| CAS | 1110781-88-8 |
| Purity | >99% |
| Chemical Name or Material | N-(3-Ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)benzamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C20H21F3N2O2 |
| Formula Weight | 378.39 |
1,162
Tocris Bioscience™ MK 0677
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High affinity ghrelin receptor agonist
| Target | Ghrelin Receptor Agonists |
|---|---|
| CAS | 159752-10-0 |
| Purity | 98% |
| Chemical Name or Material | 2-Amino-N-[(1 R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3 H-indole-3,4 '-piperidin]-1 '-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate |
| Recommended Storage | Store at -20°C |
| Synonym | Ibutamoren mesylate, L-163,191 |
| Molecular Formula | C27H36N4O5S.CH3SO3H |
| Formula Weight | 624.77 |
1,163
Tocris Bioscience™ VU 0255035
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Highly selective M1 antagonist
| CAS | 1135243-19-4 |
|---|---|
| Chemical Name or Material | N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H20N6O3S2 |
| Formula Weight | Observed MW: 432.52 |
| Assay Percent Range | >99% |
1,164
Tocris Bioscience™ L-838,417
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CAS: 286456-42-6 Molecular Formula: C19H19F2N7O
| CAS | 286456-42-6 |
|---|---|
| Molecular Formula | C19H19F2N7O |
1,165
Tocris Bioscience™ KML 29
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CAS: 1380424-42-9 Molecular Formula: C24H21F6NO7
| CAS | 1380424-42-9 |
|---|---|
| Molecular Formula | C24H21F6NO7 |
1,166
Tocris Bioscience™ Triacsin C
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Inhibitor of acyl-CoA synthetase
1,167
Tocris Bioscience™ SAHA
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CAS: 149647-78-9 Molecular Formula: C14H20N2O3
| CAS | 149647-78-9 |
|---|---|
| Molecular Formula | C14H20N2O3 |
1,168
Tocris Bioscience™ GeA-69
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Selective allosteric PARP14 inhibitor
| Target | PARP |
|---|---|
| CAS | 2143475-98-1 |
| Purity | 0.98 |
| Chemical Name or Material | N-[2-(9 H-Carbazol-1-yl)phenyl]acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H16N2O |
1,169
Tocris Bioscience™ NCT 02
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Molecular glue; induces degradation of CCNK and CDK12
| Target | Molecular Glues |
|---|---|
| CAS | 790245-61-3 |
| Purity | 0.98 |
| Chemical Name or Material | 6,7-Dihydro-N-(5-methyl-2-thiazolyl)-5 H-indeno[5,6-b]furan-3-acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H16N2O2S |
1,170
Tocris Bioscience™ DL-TBOA
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CAS: 205309-81-5 Molecular Formula: C11H13NO5
| CAS | 205309-81-5 |
|---|---|
| Molecular Formula | C11H13NO5 |